Risk factors of postoperative sexual function in patients with urethral diverticulum and their partners: A cohort study of 83 women

ABSTRACT Introduction and Objective: Several studies have focused on the treatment and recurrence of urethral diverticulum (UD). However, few investigations have addressed sexual function in patients with UD. Therefore, we sought to examine sexual function in women affected by UD. Materials and Methods: There were 108 accepted cases involving transvaginal diverticulectomy at our institution. Ultimately, 83 women were included for further analysis, only 61 of these women had sexual partners. We collected data for the Female Sexual Function Index (FSFI) from the female patients and the Male Sexual Health Questionnaire (MSHQ) from their male partners before and after surgery. Results: Preoperatively, the UD size affected the female patient's arousal and lubrication (p=0.04), and the UD location affected their satisfaction. However, no significant between-group differences were found in the total FSFI score. For all women, sexual activity improved after surgery (p=0.0087). In addition to improvements in arousal for women with a large UD, improvements in lubrication were affected by the UD size, number and shape, increases in satisfaction scores were impacted by the UD location and shape, and pain relief was linked to the UD number and shape. Analysis of the MSHQ results revealed no between-group differences among the male partners. Conclusion: Only the UD size and location affected sexual function in women with a small UD. Surgery could improve female sexual function but did not affect the sexual function of the patient's partners.

Hypertension as a risk factor for female sexual dysfunction: cross-sectional study / Hipertensão como fator de risco para disfunção sexual feminina: estudo transversal / La hipertensión como un factor de riesgo para la disfunción sexual femenina: estudio transversal

ABSTRACT Objective: to evaluate the sexual dysfunction in hypertensive patients compared to normotensive patients. Method: this was a cross-sectional study. Samples were composed of 54 hypertensive patients and 54 normotensive patients. The female sexual dysfunction was evaluated by the Female Sexual Function Index (FSFI). Results: the average FSFI score differed highly between hypertensive and normotensive patients (22.4± 7.4 versus 26.8 ±5.4, p< 0.001). Among hypertensive patients, 63% showed sexual dysfunction in opposition to 39% of normotensive patients (p=0.02). Hypertensive women had 1.67 more chances of showing the dysfunction than women with normal blood pressure. Conclusion: the sexual dysfunction prevalence is higher in hypertensive than in normotensive women hence, hypertension is a potentiator factor for female sexual dysfunction.

RESUMO Objetivo: avaliar a disfunção sexual em pacientes hipertensas em comparação com pacientes normotensas. Método: estudio transversal. Las muestras estaban compuestas por 54 pacientes hipertensos y 54 normotensos. La disfunción sexual femenina fue evaluada por el Índice de Función Sexual Femenina (FSFI). Resultados: a pontuação média do FSFI foi muito diferente entre pacientes hipertensas e normotensas (22,4 ± 7,4 versus 26,8 ± 5,4, p <0,001). Da amostra de pacientes hipertensas, 63% apresentaram disfunção sexual, ante 39% da amostra de pacientes normotensas (p=0,02). As mulheres hipertensas apresentaram 1,67 vezes mais chances de ter a disfunção do que mulheres com pressão arterial normal. Conclusão: a prevalência de disfunção sexual é maior em mulheres hipertensas do que em mulheres normotensas. Portanto, a hipertensão é um fator que potencializa a disfunção sexual feminina.

RESUMEN Objetivo: evaluar la disfunción sexual en pacientes hipertensos en comparación con pacientes normotensos. Método: estudio transversal. Las muestras estaban compuestas por 54 pacientes hipertensos y 54 normotensos. La disfunción sexual femenina fue evaluada por el Índice de Función Sexual Femenina (FSFI). Resultados: el puntaje FSFI promedio fue muy diferente entre pacientes hipertensos y normotensos (22.4±7.4 versus 26.8 ± 5.4, p<0.001). El 63% de los pacientes de la muestra de hipertensos demonstraron disfunción sexual, en oposición al 39% de la muestra de pacientes normotensos (p=0,02). Las mujeres hipertensas presentaron 1.67 más posibilidad de mostrar la disfunción que las mujeres con presión arterial normal. Conclusión: la prevalencia de disfunción sexual es mayor en mujeres hipertensas que en mujeres normotensas. Entonces, la hipertensión es un potenciador de la disfunción sexual femenina.

Comparison of the Kelly's plication and TOT simultaneously with vaginal hysterectomy, on the incontinence, and sexual functions

ABSTRACT Purpose: To compare the effect of vaginal hysterectomy-anterior/posterior colporrhaphy with Kelly's plication(VH-KP), versus vaginal hysterectomy-anterior/posterior colporrhaphy-transobturator tape(VH-TOT) surgeries on incontinence, quality of life, and sexual functions in patients with pelvic organ prolapse(POP), and concurrent obvious stress urinary incontinence(SUI). Materials and Methods: Between 2013 and 2017, fifty patients treated with VH-KP(n = 25), and VH-TOT(n = 25) due to POP and SUI, were evaluated prospective consecutively. Age, parity, duration of urinary incontinence, and the daily pad use were recorded. Patients were filled "rinary Distress Inventory-6(UDI-6)", "Incontinence Impact Questionnaire 7(IIQ-7)" and "Index of Female Sexual Function(IFSI)" questionnaire forms at preoperatively, and postoperative 6th month. No usage of pads was accepted as subjective cure rate. Intraoperative, and postoperative complications were noted. Results: There was no statistically significant difference between two groups, for the mean age of the patients, parity, duration of SUI, and the daily pad use, preoperatively (p > 0.05). Decreased UDI-6 scores, IIQ-7 scores and daily pad usage, and increased IFSF scores were found statistical significantly in each group, at the postoperative 6 th month (p < 0.05). However, VH-TOT group had higher improvement rates, on UDI-6 scores (69.5% vs 63.0%, p = 0.04). In addition, it was notable that the the rates of the patients had IFSF scores ≥ 25 was higher in VH-KP group (p = 0.05). Four (16%) patients had recurrent SUI in the VH-KP group (p = 0.039) and vaginal extrusion occurred in 2 (8%) patients in the VH-TOT group (p = 0.153), postoperatively. Conclusions: Although the effects of VH-TOT surgery are superior to conventional methods for incontinence and quality of life; negative effects on sexual functions are notable. In addition, although recurrence rates of TOT are low, complications such as vaginal extrusion are accompanied by drawbacks of mesh usage.

Analysis of sexual function of patients with dermatomyositis and polymyositis through self-administered questionnaires: a cross-sectional study / Análise da função sexual de pacientes com dermatomiosite e polimiosite através de questionários autoaplicados: um estudo transversal

Abstract Introduction: To date, there are no descriptions in the literature on gynecologic and sexual function evaluation in female patients with dermatomyositis (DM) and polymyositis (PM). Objective: To assess sexual function in female patients with DM/PM. Patients and methods: This is a monocentric, cross-sectional study in which 23 patients (16 DM and 7 PM), with ages between 18 and 40 years, were compared to 23 healthy women of the same age group. Characteristics on sexual function were obtained by applying the questionnaires Female Sexual Quotient (FSQ) and Female Sexual Function Index (FSFI) validated for the Brazilian Portuguese language. Results: The mean age of patients was comparable to controls (32.7 ± 5.3 vs. 31.7 ± 6.7 years), as well as the distribution of ethnicity and socioeconomic class. As for gynecological characteristics, patients and healthy controls did not differ with respect to age at menarche and percentages of dysmenorrhea, menorrhagia, premenstrual syndrome, pain at mid-cycle, mucocervical secretion, and vaginal discharge. The FSQ score, as well as all domains of the FSFI questionnaire (desire, arousal, lubrication, orgasm and satisfaction), were significantly decreased in patients vs. controls, with 60.9% of patients showing some degree of sexual dysfunction. Conclusions: This was the first study to identify sexual dysfunction in patients with DM/PM. Therefore, a multidisciplinary approach is essential for patients with idiopathic inflammatory myopathies, in order to provide prevention and care for their sexual life, providing a better quality of life, both for patients and their partners.

Resumo Introdução: Até o presente momento, não há descrições na literatura da avaliação ginecológica e da função sexual em pacientes do sexo feminino com dermatomiosite (DM) e polimiosite (PM). Objetivos: Avaliar a função sexual em pacientes do sexo feminino com DM/PM. Casuística e métodos: Estudo transversal unicêntrico em que 23 pacientes (16 DM e sete PM), entre 18 e 40 anos, foram comparadas com 23 mulheres saudáveis, com a mesma faixa etária. As características sobre a função sexual foram obtidas por meio da aplicação dos questionários Female Sexual Quotient (FSQ) e Female Sexual Function Index (FSFI) validados para a língua portuguesa do Brasil. Resultados: A média de idade das pacientes foi comparável à dos controles (32,7 ± 5,3 vs. 31,7 ± 6,7 anos), assim como a distribuição de etnia e da classe socioeconômica. Quanto às características ginecológicas, pacientes e controles saudáveis não apresentaram diferenças em relação à idade na menarca e às porcentagens de dismenorreia, menorragia, síndrome pré-menstrual, dor no meio do ciclo, secreção mucocervical e corrimento vaginal. O escore de pontuação do FSQ, assim como todos os domínios do questionário do FSFI (desejo, excitação, lubrificação, orgasmo e satisfação), estavam significantemente diminuídos nas pacientes comparativamente com os controles, 60,9% das pacientes apresentavam algum grau de disfunção sexual. Conclusões: Este foi o primeiro estudo que identificou disfunção sexual nas pacientes com DM/PM. Assim, uma abordagem multidisciplinar é essencial para pacientes com miopatias inflamatórias idiopáticas para fornecer medidas de prevenção e cuidados para sua vida sexual e propiciar uma melhor qualidade de vida das pacientes e de seus parceiros.

Female urinary incontinence and sexuality

ABSTRACT Urinary incontinence is a common problem among women and it is estimated that between 15 and 55% of them complain of lower urinary symptoms. The most prevalent form of urinary incontinence is associated with stress, followed by mixed urinary incontinence and urge urinary incontinence. It is a symptom with several effects on quality of life of women mainly in their social, familiar and sexual domains. Female reproductive and urinary systems share anatomical structures, which promotes that urinary problems interfere with sexual function in females. This article is a review of both the concepts of female urinary incontinence and its impact on global and sexual quality of life. Nowadays, it is assumed that urinary incontinence, especially urge urinary incontinence, promotes anxiety and several self-esteem damages in women. The odour and the fear of incontinence during sexual intercourse affect female sexual function and this is related with the unpredictability and the chronicity of incontinence, namely urge urinary incontinence. Female urinary incontinence management involves conservative (pelvic floor muscle training), surgical and pharmacological treatment. Both conservative and surgical treatments have been studied about its benefit in urinary incontinence and also the impact among female sexual function. Unfortunately, there are sparse articles that evaluate the benefits of female sexual function with drug management of incontinence.

Female sexual function following a novel transobturator sling procedure without paraurethral dissection (modified-TOT)

ABSTRACT Purpose To determine whether there is a difference in sexual function after modified and classical TOT procedures. Materials and Methods Of the 80 sexually active women with SUI, 36 underwent an original outside-in TOT as described by Delorme, and 44 underwent modified TOT procedure, between 2011 and 2015. The severity of incontinence and sexual function were evaluated using International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) and Female Sexual Function Index (FSFI) questionnaires preoperatively and 3 months after surgery. Results The postoperative ICIQ-SF score was significantly lower than the preoperative ICIQ-SF score in both groups (p=0.004 for modified TOT and p=0.002 for classical TOT). There was no significant difference in the ICIQ-SF score reduction between the two groups (14.1±2.1 vs. 14.4±1.9; p=0.892). Complication rates according to the Clavien-Dindo classification were also similar in both groups. In both groups, difference between preoperative and postoperative FSFI scores revealed a statistically significant improvement in all domains. Comparison of postoperative 3-month FSFI scores of modified and classical TOT groups showed statistically significant differences in arousal, lubrication and orgasm domains. Desire, satisfaction, pain and total FSFI scores did not differ significantly between two groups. Conclusion The modified TOT technique is a simple, reliable and minimal invasive procedure. The cure rate of incontinence and complication rates are the same as those of the classical TOT technique. However, due to the positive effects of minimal tissue damage on sexual arousal and orgasmic function, modified TOT has an advantage over the classical TOT.

Impacto do sobrepeso na disfunção sexual feminina: revisão da literatura / Impact of overweight in sexual dysfunction female: review of literature

Este estudo objetiva revisar a literatura sobre o impacto da obesidade/sobrepeso nas disfunções sexuais femininas. A pesquisa foi realizada nas bases de dados SciELO, LILACS e Scholar, utilizando os descritores "disfunção sexual" e "sobrepeso" ou "obesidade" em português e os seus equivalentes em inglês ("sexual dysfunction" e "overweight" ou "obesity") em artigos publicados entre 2005 e 2015. Os critérios de exclusão foram: ser somente resumo e artigo completo não ser disponível online ou somente estudo de disfunção sexual masculina. Foram encontrados 98 artigos na base de dados SciELO, 975 na base de dados LILACS e 297 no Scholar; destes foram incluídos apenas sete artigos tendo em vista que todos os outros apresentavam algum critério de exclusão. A maioria dos artigos avaliados foi positiva ao relacionar a disfunção sexual em mulheres e a obesidade/sobrepeso. Alguns artigos também relacionaram a síndrome metabólica com a disfunção sexual feminina (DSF), sendo essa síndrome muito relacionada com a obesidade, principalmente a obesidade visceral, um fator de risco cardiovascular. Observamos pouca diferença no instrumento utilizado pelos autores, a maioria utilizando o Female Sexual Function Index (FSFI). Pode-se concluir que s índices de sobrepeso e obesidade vêm crescendo significativamente no mundo, e, após este trabalho, observarmos forte e consistente relação entre a disfunção sexual e o excesso de peso. O FSFI demonstrou ser um instrumento eficaz no estudo da DSF. Porém, nenhum estudo pode comprovar uma relação de causa e efeito, pois se tratam de estudos transversais. Não foi encontrado nenhum estudo de intervenção observando a relação entre a perda de peso e a melhora na função sexual de mulheres, o que corroboraria a hipótese de que a obesidade seria um fator importante na DSF.(AU)

This study aims to review the literature on the impact of obesity/overweight in sexual dysfunctions. The survey was conducted in databases SciELO, LILACS and Scholar, using the descriptors "sexual dysfunction" and "obesity/overweight" in English and their synonyms in Portuguese ("disfunção sexual" and "obesidade" or "sobrepeso"), in scientific papers published between 2005 and 2015. Exclusion criteria: being an abstract, full text not available online or only related to male sexual dysfunction. 98 articles were found in the SciELO database, 975 in the LILACS database and 297 in Scholar; from these were included only seven articles, given that everyone else had some requirement of the exclusion criteria. Most reviewed articles found positive association between sexual dysfunction in women and obesity/overweight. Some articles also linked the metabolic syndrome with female sexual dysfunction, which is closely related with obesity, especially visceral obesity, and is a cardiovascular risk factor. There was little difference in the methodology used by the authors, most of them using the Female Sexual Function Index (FSFI). It can be concluded that overweight and obesity rates have been significantly growing in the world, and, after this work, we observe strong and consistent relationship between sexual dysfunction and overweight. The FSFI proved to be an effective tool in the study of female sexual dysfunction. However, no study could prove a cause-effect relationship, since they were cross-sectional studies. No intervention study observing the relationship between weight loss and sexual function improvement in women was found, which would corroborate the hypothesis that obesity could be an important factor in female sexual dysfunction.(AU)

Validation and cross-cultural adaptation of sexual dysfunction modified scale in multiple sclerosis for Brazilian population / Validação e adaptação transcultural da escala modificada de disfunção sexual em esclerose múltipla na população brasileira

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS). These patients suffer from various comorbidities, including sexual dysfunction (SD). The lesions of MS may affect regions of the CNS along the pathway of sexual response. The Multiple Sclerosis Intimacy and Sexuality Questionnaire-19 (MSISQ-19) is a scale that assesses sexual dysfunction. Adapt and validate the MSISQ-19 to Brazilian patients with MS. 204 individuals were evaluated, 134 patients with MS and 70 healthy persons for the control group. It was determined reproducibility, validity, internal consistency and sensitivity of the MSISQ-19-BR. Among patients with MS, 54.3% of male and 71.7% of female presented some kind of SD. In the control group the results were 12.5% and 19.5%, respectively. The MSISQ-19-BR is reproducible, reliable and valid for the Brazilian population and may be used as a tool for assessing the impact of sexual dysfunction in patients with MS.

A esclerose múltipla (EM) é uma doença crônica inflamatória do sistema nervoso central (SNC). Esses pacientes sofrem de várias comorbidades, incluindo a disfunção sexual. As lesões da EM podem afetar varias regiões do SNC inclusive a via de resposta sexual. O Multiple Sclerosis Intimacy and Sexuality Questionnaire-19 (MSISQ-19) é uma escala de avaliação da disfunção sexual. Adaptar e validar o MSISQ-19 para os pacientes brasileiros com EM. 204 indivíduos foram avaliados, 134 pacientes com EM e 70 controles saudáveis. Foi determinado à reprodutibilidade, validade, consistência interna e a sensibilidade do MSISQ-19BR. Entre os pacientes com EM, 54,3% dos homens e 71,7% das mulheres apresentam algum tipo de DS. No grupo controle os resultados foram 12,5% e 19,5%, respectivamente. O MSISQ-19BR foi reprodutível, confiável e validade para a população brasileira e pode ser usado como uma ferramenta de avaliação do impacto da disfunção sexual nos pacientes com EM.

Comparação da qualidade de vida em gestantes com disfunção sexual / Comparison of quality of life in women with sexual dysfunction

OBJETIVO: Investigar a relação entre função sexual e qualidade de vida em mulheres grávidas, residentes em duas cidades do Nordeste. MÉTODOS: A amostra constituiu-se de 207 gestantes. A coleta de dados foi feita por meio da aplicação de questionário contendo questões sobre dados sociodemográficos, ginecológicos e obstétricos, conhecimento corporal e sexual. A qualidade de vida foi avaliada através da aplicação do Índice de Qualidade de Vida Ferrans & Powers (IQV Ferrans e Power). A função sexual foi avaliada por meio do Índice de Função Sexual Feminina (IFSF). Foram realizados os testes estatísticos de Shapiro-Wilk, Mann-Whitney e Wilcoxon para análise dos dados coletados. RESULTADOS: As gestantes avaliadas apresentaram idade mediana de 30 anos (quartil 26-33 anos) e estavam aproximadamente na 26a semana gestacional. Observou-se diminuição significativa da frequência mensal do relacionamento sexual do casal, que passou de uma mediana de 12 para 4 vezes por mês (Z =-10,56; p<0,001). A disfunção sexual se mostrou presente em 35,7% das gestantes avaliadas, e a qualidade de vida dessas foi inferior quando comparada àquelas com função sexual sem alteração (Z=-2,87; p=0,004). CONCLUSÃO: Os resultados do presente estudo mostram que a disfunção sexual afetou negativamente a qualidade de vida de mulheres grávidas, devendo ser um aspecto relevante para ser avaliado durante as consultas de pré-natal. .

PURPOSE: To investigate the relationship between sexual function and quality of life in pregnant women living in two cities of Northeastern Brazil. METHODS: The sample consisted of 207 pregnant women. The data were collected through a questionnaire containing questions about socio-demographic, gynecological and obstetrical data, body and sexual knowledge. Quality of life was assessed by applying the Ferrans & Powers Quality of Life Index (QLI Ferrans and Power). Sexual function was assessed using the Female Sexual Function Index (IFSF). Data were statistically analyzed using the Shapiro-Wilk, Mann-Whitney and Wilcoxon tests. RESULTS: The pregnant women studied had a median age of 30 years (quartile 26-33 years) and were approximately at the 26th gestational week. A significant decrease in the monthly frequency of sexual relations of the couple was observed, with a median of 12 to 4 times per month (Z=-10.56; p<0.001). Sexual dysfunction was detected in 35.7% of the pregnant women studied, whose quality of life was lower when compared to women with unchanged sexual function (Z=-2.9; p=0.004). CONCLUSION: The results of this study show that sexual dysfunction negatively affected the quality of life of pregnant women, and this should be an important aspect for review during prenatal consultations. .

Quality of life after high-dose-rate brachytherapy monotherapy for prostate cancer

Purpose There is little information in the literature on health-related quality of life (HRQOL) changes due to high-dose-rate (HDR) brachytherapy monotherapy for prostate cancer. Materials and Methods We conducted a prospective study of HRQOL changes due to HDR brachytherapy monotherapy for low risk or favorable intermediate risk prostate cancer. Sixty-four of 84 (76%) patients who were treated between February 2011 and April 2013 completed 50 questions comprising the Expanded Prostate Cancer Index Composite (EPIC) before treatment and 6 and/or 12 months after treatment. Results Six months after treatment, there was a significant decrease (p<0.05) in EPIC urinary, bowel, and sexual scores, including urinary overall, urinary function, urinary bother, urinary irritative, bowel overall, bowel bother, sexual overall, and sexual bother scores. By one year after treatment, EPIC urinary, bowel, and sexual scores had increased and only the bowel overall and bowel bother scores remained significantly below baseline values. Conclusions HDR brachytherapy monotherapy is well-tolerated in patients with low and favorable intermediate risk prostate cancer. EPIC urinary and sexual domain scores returned to close to baseline 12 months after HDR brachytherapy. .

Treatments for invasive carcinoma of the cervix: what are their impacts on the pelvic floor functions?

Aims: Describe the impact of surgery, radiotherapy and chemoradiation in the pelvic floor functions in cervical cancer patients. Materials and Methods: A prospective study with women submitted to radical hysterectomy (RH) (n = 20), exclusive radiotherapy (RT) (n = 20) or chemoradiation (CT/RT) (n = 20) for invasive cervical cancer. Urinary, intestinal and sexual function, as well as vaginal length and pelvic floor muscle contraction were evaluated. Comparisons between groups were performed by Kruskal-Wallis and Chi-square tests (p < 0.05). Results: The groups were similar in stress urinary incontinence incidence (p = 0.56), urinary urgency (p = 0.44), urge incontinence (p = 0.54), nocturia (p = 0.53), incomplete bowel emptying (p = 0.76), bowel urgency (p = 0.12) and soilage (p = 0.43). The CT/RT group presented a higher urinary frequency (p < 0.001) and diarrhea (p = 0.025). Patients in the RH group were more sexually active (p = 0.01) and experienced less dyspareunia (p = 0.021). Vaginal length was shorter in RT group (5.5 ± 1.9cm) and CT/RT(5.3 ± 1.5 cm) than in the RH group (7.4 ± 1.1 cm) (p < 0.001). Pelvic floor muscle contraction was similar (p = 0.302). Conclusions: RT and CT/RT treatment for cervical carcinoma are more associated to sexual and intestinal dysfunctions. .

Função sexual feminina: aspectos normais e patológicos, prevalência no Brasil, diagnóstico e tratamento / Female sexual function: normal and pathological aspects, prevalence in Brazil, diagnosis and treatment

A função sexual representa um componente importante da saúde e da qualidade de vida. O objetivo deste artigo foi descrever aspectos normais e patológicos da função sexual feminina e expor os métodos diagnósticos e terapêuticos, abordando a prevalência no Brasil. Para isso, foi realizada uma revisão da literatura, de artigos publicados entre 1985 e 2012, dos quais foram selecionados 56, indexados no PubMed/Medline e SciELO. Os achados indicam que as disfunções sexuais nas mulheres apresentam etiologia multifatorial e são pouco estudadas na população brasileira. A terapêutica deve ser adaptada de acordo com a necessidade da paciente e desenvolvida por uma equipe multidisciplinar

Sexual function represents an important component of health and quality of life. The purpose of this article was to describe normal and pathological aspects of female sexual function and expose the diagnostic and therapeutic methods, addressing the prevalence in Brazil. For this, was realized a literature review, of articles published from 1985 to 2012, which 56 were selected, indexed in PubMed/Medline and SciELO. The findings indicate that female sexual dysfunctions have multifactorial etiology and are not very well studied in the Brazilian population. Therapy should be tailored according to the needs of the patient and done by a multidisciplinary team

La hipersexualidad: nuevos aportes a su conceptualización y tratamiento / Hypersexuality: new contributions to the conceptualization and treatment

Objetivo: este artículo revisa el concepto de hipersexualidad, las condiciones asociadas a dicho comportamiento así como los tratamientos indicados para el mismo.Métodos: llevamos a cabo una búsqueda en internet de artículos en lenguaje inglés publicados en los últimos 20 años (hipersexualidad, sexualidad humana, comportamiento hipersexual, ninfomanía).Resultados: la hipersexualidad es un cambio en las formas e incremento en la frecuencia de los comportamientos sexuales. La etiología de la hipersexualidad es compleja e involucra una variedad de mecanismos fisiológicos y psicológicos. Puede ser idiopática o el resultado final de muchos procesos de enfermedad subyacentes. La disfunción del lóbulo frontal y de otras áreas cerebrales puede conducir a la desinhibición en el comportamiento sexual y a hipersexualidad; esta condición también puede ser el resultado de otros trastornos neurológicos, psiquiátricos o efectos secundarios de medicamentos. Cuando la causa subyacente puede ser tratada, el comportamiento sexual desinhibido cesa. Conclusión: la hipersexualidad puede ocasionar conductas de difícil manejo, pero los métodos farmacológicos pueden controlar de manera exitosa estos comportamientos en la mayoría de los pacientes.

Objective: This article reviews the concept of hypersexuality, the conditions attached to such behavior and the treatments prescribed for it. Methods: We conducted an internet search for English-language articles published over the past 20 years (Hypersexuality, human sexuality, hypersexual behavior, Nymphomania). Results: Hypersexuality is a change in the ways and an increase in the frequency of the sexual behaviors. The etiology of hypersexuality is complex and involves a variety of physiological and psychological mechanisms. It may be idiopathic or the final result of many underling disease processes. The dysfunction of the frontal lobe and other brain areas can lead to the disinhibition in the sexual behavior and hypersexuality; this condition can also be the result of other neurological and psychiatric disorders or an adverse effect of medications. When the underlying cause can be treated, the uninhibited sexual behavior ceases. Conclusion: Hypersexuality can cause unmanageable behavior, but pharmacological methods can successfully control this behavior in most patients.

Sexual dysfunctions among people living with aids in Brazil

INTRODUCTION: Sexual dysfunction symptoms in patients with HIV have not been fully investigated in Brazil. OBJECTIVES: To investigate the association between sexual dysfunction symptoms and AIDS among participants in the Brazilian Sex Life Study. METHODS: The Brazilian Sex Life Study is a cross-sectional population study. The participants answered an anonymous self-responsive inquiry. It was applied to a population sample in 18 large Brazilian cities. Answers given by those who reported having AIDS (75) were compared with those who reported not having AIDS (control; 150). This was a case-control study nested in a cross-sectional population study. RESULTS: In females, AIDS was associated with "sexual inactivity over the last 12 months" and "does not maintain sexual arousal until the end of the sex act" (P < 0.05) after adjusting for race and thyroid disease. Compared to the control group, men with AIDS had more difficulty becoming sexually aroused (they required more help from their partner to begin the sex act, they required longer foreplay than they wished, they reported losing sexual desire before the end of the sex act, and they required longer to ejaculate than they desired) (P < 0.05). After adjusting for sexual orientation, sex hormone deficiency, depression, and alcoholism, only "does not have sexual desire," "have longer foreplay," and dyspareunia were associated with AIDS. DISCUSSION AND CONCLUSIONS: The results support the hypothesis that sexual dysfunctions are associated with AIDS. Men with AIDS need more time and stimulation to develop a sexual response, and a significant portion (37 percent) of women with AIDS reported sexual inactivity over the last 12 months.

Trastornos de la conducta eyaculatoria (Tce) en una consulta privada de urosexología / Alterations of the ejaculatory behavior in a private urological practice

Objetivo: describir los trastornos de la conducta eyaculatoria que se presentan en una consulta urológica orientada a la sexología y unificar en grupos los diagnósticos relacionados con la eyaculación en la denominación única "Trastornos de la conducta eyaculatoria"(TCE). Materiales y métodos: estudio descriptivo a partir de una base de datos de 3460 pacientes atendidos entre el 8 de agosto de 1994 y el 3 de abril del 2008 en Medellín. Se dividió la población en tres grupos de TCE según el motivo de su consulta: trastornos eyaculatorios de volumen (hipoespermia vs hiperespermia), trastornos eyaculatorios de tiempo (eyaculación precoz vs retardada o aneyaculación), trastornos eyaculatorios de sensación (anorgasmia o eyaculación anhedónica vs eyaculación dolorosa). Adicionalmente el grupo de pacientes con eyaculación precoz se subdividió en eyaculación precoz primaria y secundaria según el momento en que comenzó su disfunción en la vida sexual. La investigación se hizo respetando los principios éticos, se guarda confidencialidad de la información y no se identifica a los pacientes. Los resultados se presentan en número absoluto y proporción y en media y desviación estándar según el tipo de variable. Conclusión: "Trastornos de la conducta eyaculatoria (TCE)" es un concepto apropiado para englobar diferentes diagnósticos relacionados con alteraciones de la eyaculación que se pueden dividir en tres grupos para su estudio: TCE de volumen, TCE de tiempo y TCE de sensación. Es posible que un grupo de TCE esté relacionado con un síndrome de isquemia o ateroesclerosis pélvica que tiene como componentes adicionales la disfunción eréctil (DE) y los síntomas urinarios bajos (SUBS). De los pacientes con eyaculación precoz, los secundarios tienen mayor posibilidad de pertenecer a los TCE relacionados con la edad como la isquemia pélvica. Para el futuro son necesarios estudios adicionales con diseñosmetodológicos más estrictos para comprender mejor esta enfermedad

Sexual functioning in postmenopausal women not taking hormone therapy in the Gynecological and Menopause Clinic, Songklanagarind Hospital measured by Female Sexual Function Index questionnaire.

OBJECTIVE: To study sexual functioning and attitudes towards sexuality in postmenopausal women. MATERIAL AND METHOD: A cross-sectional study was conducted among 219 healthy postmenopausal women with a uterus, aged 45-55 years, and not taking hormone therapy, who attended the gynecological and menopause clinic, Songklanagarind Hospital. The Female Sexual Function Index (FSFI) questionnaire was used as the instrument. RESULTS: The median age at enrollment and menopause age of women were 52 and 49, respectively. All the women had engaged in sexual intercourse. Sixty nine percent reported being sexually active once or twice in the previous four weeks, 27.9% three to four times and 3.1% more than four times. The mean total FSFI score was 20.4 while the proportion of women with female sexual dysfunction based on FSFI overall scores of 26.5 or less was 82.2%. Almost all the women displayed a positive attitude towards sexuality. Ninety six percent reported having sex in menopause as a natural normal part of life, 95% regarded having sex to make their partner happy whereas 77% regarded sex as a way to make themselves happy. CONCLUSION: Sexual dysfunction in postmenopausal women was rather high. However, they were still satisfied with their sexual relationship and had a positive attitude towards sexuality.

The short-term effect of surgical treatment for stress urinary incontinence using sub urethral support techniques on sexual function

OBJECTIVES: To evaluate the impact of surgical treatment of stress urinary incontinence on the sexual function of women and to identify whether such treatment can improve their sexual function and overall quality of life. MATERIALS AND METHODS: 64 heterosexual women with such indication were studied using the Female Sexual Function Index (FSFI) questionnaire, modified by introducing one question to evaluate the impact of urine loss. This was applied preoperatively and six months after surgery. RESULT: Among these 64 patients, 60.94 percent had regular sexual activity, while 39.06 percent did not. Among sexually active patients, 59 percent had urine loss during sexual intercourse and, of these, 87 percent had urine losses in half or more of sexual relations. There were no statistically significant differences in assessments of desire, arousal, lubrication, orgasm, satisfaction and pain, or in totaling the scores, between the preoperative period and six months after surgical treatment. However, the scores for urine losses during sexual intercourse were significantly better after the operation. CONCLUSIONS: Analysis of the results allowed the following conclusions to be reached: Urine lost during sexual activity was frequent among patients with stress urinary incontinence. Suburethral support surgery did not jeopardize sexual activity. Patients cured of stress urinary incontinence did not present improvement in sexual function.

Permanência das representações do gênero em sexologia: as inovações científica e médica comprometidas pelos estereótipos de gênero / Permanence of gender stereotypes in sexology: when scientific innovations are challenged by traditional gender stereotypes

Numerosas mudanças surgiram no domínio da pesquisa em sexologia, notadamente no que concerne à função e disfunções sexuais e seus tratamentos. A disfunção erétil foi reconceitualizada como uma disfunção com origem orgânica, uma transformação em relação às abordagens anteriores acerca da impotência psicogênica, desenvolvidas nos anos 1960 e 1970. Essa mudança se baseia em muitas descobertas científicas e no avanço farmacológico realizado sob influência de urologistas norte-americanos. A disponibilização no mercado do sildenafil, em 1998, acionou novos tipos de tratamentos, centrados na atividade peniana. Os mesmos grupos de urologistas passaram recentemente a repensar as "disfunções sexuais femininas" segundo o mesmo modelo orgânico da função sexual. Novos produtos farmacêuticos estão em testagem clínica, tendo em vista a proposta de tratamentos da nova categoria de transtornos sexuais. A colocação no mercado do sildenafil não provocou reações contrárias às novas abordagens dos transtornos sexuais masculinos. Inversamente, o surgimento de novos conceitos da função sexual feminina suscita importantes debates. O British Medical Journal veiculou uma discussão, estabelecendo que a função sexual feminina não possuía origem orgânica, mas fundava-se em fatores psicológicos e relacionais da atividade sexual das mulheres. O debate centrou-se na "simplicidade" da sexualidade masculina, em oposição à "complexidade" da sexualidade feminina. Este artigo apresenta a analisa as novas concepções da função sexual masculina e feminina, e evidencia a permanência de estereótipos tradicionais da sexualidade masculina e feminina, e sua influência sobre as pesquisas científicas mais avançadas nessa esfera1.

Major changes have occurred in male and female sexual function/dysfunction research and treatments. Male erectile dysfunction has been re-conceptualized as an organic dysfunction, which marks a dramatic shift from previous conceptions of psychogenic impotence developed during the 60' and the 70's. This shift is based on major scientific discoveries, and pharmacological advances that took place since the early 80's under the influence of North American urologists. The release of sildenafil in 1998 was the corner stone of a new paradigm of treatments focusing on male penile activity, far remote from any psychological approaches. More recently, the same group of urologists started to reconsider Female Sexual Dysfunction using the same organic/biological model of sexual function. New pharmaceutical products are currently under trial for the treatment of this new category of female sexual disorder. But as opposed to the absence of public adverse reaction to the development of this approach of male function, many voices raised to oppose this new conception of female function. A major discussion took place in the British Medical Journal stating that female sexual function was not organically driven, but rather determined by the social, psychological and interpersonal context of female sexual activity and relations. One of the major dimensions of this discussion opposed the so-called "simplicity" of male sexual function to the "complexity" of female sexual function. This paper demonstrates the permanence of traditional social scripts of male and female sexuality and their influence in the most advanced scientific research in this field.

Penile vibratory threshold changes with various doses of SS-cream in patients with primary premature ejaculation

SS-cream made with extracts from natural products is a topical agent for treating premature ejaculation (PE). In order to elucidate the penile vibratory threshold changes and clinical effects of various doses of SS-cream, 53 patients with primary PE were investigated in a double-blind randomized placebo-controlled study. The mean age was 37.3 +/- 6.4 years and mean ejaculatory latency was 1.37 +/- 0.52 minutes. Neither the patients nor their sexual partners were satisfied with their sexual lives. Vibratory threshold at the glans penis, penile shaft, scrotum and index finger were measured using a biothesiometer twice during the screening period and three times one hour after the application of respective creams (SS-cream 0.05, 0.10. 0.15, 0.20 gm and placebo 0.10 gm) on the glans penis according to the order of the allocation table in a randomized fashion. The efficacy of SS-cream was defined as when the vibration threshold increased by more than 4 microns compared to the value tested during the screening period. The vibratory thresholds at the glans penis increased significantly in a dose-dependent manner after the application of various doses (0.05, 0.10, 0.15, 0.20 gm) of SS-cream (p < 0.001), and the efficacy of SS-cream on the penile vibration threshold increased according to the increased dosage (penile shaft: 48.4, 51.6, 54.8, 64.5%, glans penis: 58.1, 67.7, 77.4, 83.9%, respectively). With these results, we concluded that SS-cream increased the penile sensory threshold dose dependently, and therefore it is clinically effective for treating the heightened penile sensory response in patients with PE.

Alteraçöes sexuais na epilepsia: resultados de uma avaliaçäo multidisciplinar / Sexual disorders in epilepsy: results of a multidisciplinary evaluation

Onze pacientes do sexo masculino com epilepsia e queixa de alteração foram submetidos a avaliação multidisciplinar. A média de idade foi 27 anos (20-34), a duração média da epilepsia foi 19 anos (0,5-32) e a frequência média das crises foi duas por semana (0-7). Dez pacientes apresentavam crises parciais e um, mioclônicas. Dez pacientes recebiam drogas antiepilépticas (difenil-hidantoína - 1, carbamazepina - 8, clonazepam -3, clobazam -2, valproato -3, vigabatrina -1). Segundo os critérios do DSM III - R, as queixas foram disfunção erétil (9), redução da libido (4), froteurismo (4), inibição do orgasmo (3), ejaculação precoce (3), fetichismo (2), voyeurismo (2), exibicionismo (2), pedofilia (1) e aversão sexual (1). A avaliação endocrinológica mostrou hipogonadismo hipogonadotrófico em dois pacientes. A avaliação urológica revelou disfunção erétil orgânica em outros dois. Em um paciente a alteração sexual foi considerada psicogênica. Em seis pacientes não foi possível estabelecer diagnóstico etiológico definitivo. Este estudo mostra que a alteração da sexualidade na epilepsia é multifatorial e necessita de abordagem multidisciplinar.